WHAT IS DHT’S ROLE IN BALDNESS
Male pattern baldness, or androgenetic alopecia, is the most common type of hair loss among males. Hormonal factors appear to play a role, in particular, a male sex hormone known as dihydrotestosterone (DHT).
Facts on DHT
DHT is an androgen and helps give males their male characteristics
DHT is thought to cause hair follicles to miniaturize, and this contributes to male pattern baldness
By the age of 50 years, 50% of the male population will probably experience hair loss mediated by DHT
Treatments that block DHT may help prevent hair loss
hOW DHT CAUSES HAIR LOSS
DHT contributes to shortening the growth phase (anagen) and lengthening the resting phase (telogen).
Essentially encouraging your hair follicles to stop growing altogether.
THE ROLE OF 5-ALPHA-REDUCTASE
5-alpha-reductase (5-AR) is the enzyme that converts testosterone into the much more potent androgen, DHT.
If 5-AR levels increase, more testosterone will be converted into DHT, and greater hair loss will result.
There are two versions of 5-AR:
type 1 and 2 enzymes
Type 1 is predominantly found in sebaceous glands that produce the skin’s natural lubricant, sebum.
Type 2 mostly sits within the genitourinary tract and hair follicles.
Type 2 is considered more important in the process of hair loss.